SMALL MOLECULE PREVENTS DECAY CAUSING BIOFILM FROM STICKING TO TEETH

SMALL MOLECULE PREVENTS DECAY CAUSING BIOFILM FROM STICKING TO TEETH   dentist Albuquerque

Researchers at the University of Alabama synthesized a small molecule (#G43) that inhibits Streptococcus mutans from forming decay-causing biofilm on a subject’s teeth.  The molecule is not bacteriocidal, but simply prevents S. mutans biofilm from forming on the teeth.

Biofilm is a loose organization of bacteria that form on moist surfaces or under water.  The slick film at the bottom of your cat’s water dish is biofilm.  Most biodilm is harmless, but when Strep mutans is the major bacterium involved in the formation of biofilm it can lead to dental decay.  The offending glucan biofilm is made by three enzymes produced by S. mutans.

The molecule developed in this research is specific for Strep mutans, so it has no effect on other strains of bacteria, which were able to form their own harmless versions of biofilm in the presence of the treatment molecule.

Test results were performed on mice.  More testing will be necessary to see if the result is replicated on human teeth.  An article on this research in sciencedaily.com can be read by clicking here.

We strive to stay current with treatment modalities that can reduce the incidence of decay on our patients.  We will let you know when newer forms of decay prevention are discovered.  We care about your health

Clark Family Dental  87114

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